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Doctor's Best SAMe 400, 400 mg, 30 Tablets

SKU# 753950001510

List Price: $39.99

$31.99

Save: $8.00 (20% off)

($1.07/serving)

Availability: In stock


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SAMe 400
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Product Highlights
  • Features the Highest Available Percentage of the Active S,S Form of SAMe
  • May Enhance Cartilage Protection & Promote Synthesis of Connective Tissue
  • Clinically Shown to to Enhance Mobility & Movement & Promote Joint Comfort
  • Promotes the Synthesis of Neurotransmitters to Support Mood & Cognitive Health
SKU 753950001510
Quantity 30 Tablets 
Serving Size 1 Enteric Coated Tablet
Servings Per Container 30
Potency 400 mg
Dietary Needs Dairy Free, Free of Artificial Flavors, Gluten Free, Soy Free, Vegetarian, Wheat Free, Yeast Free
Directions Take 1 Docter's Best SAMe tablet daily away from food, or as directed by a health care professional. Do not chew or crush tablet.
Warnings Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.
Ingredients S-Adenosyl Methionine (from 800 mg of SAM-e tosylate disulfate)…for product label information including a complete list of ingredients, click all product images above.
Other Ingredients Cellulose Gel, Methacrylic Acid Copolymer, Compritol 888ATO, Talc, Triethyl Citrate, Titanium Dioxide, Magnesium Stearate, Mannitol, Glycerol, Palmitostearate, Silica, Medium Chain Triglycerides, Sodium Starch Glycolate and Iron Oxide.
Product Details

Doctor's Best Double-Strength SAMe 400 contains 400 mg of active SAMe in each tablet. Doctor's Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none.

S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.

Supplementing with SAMe - The manufacturing process of SAMe yields two forms, the S,S and the R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in Double-Strength SAMe 400 is processed to yield the highest available percentage of the active pure S,S form on the market.

SAMe and Joint Function - SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential components of connective tissue. Clinical studies show an ability of SAMe to enhance mobility and movement, and promote joint comfort.

SAMe and Neural Health - SAMe-catalyzed methylation reactions promote the synthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function.

SAMe and Liver Function - SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver protection. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.

Science-Based Nutrition

Dietary Supplement with 400 mg Active S-Adenosyl Methionine Per Tablet

Enhances Mood & Neural Function

Promotes Joint Comfort & Mobility

Supports Liver Health & Detoxification

Pharmaceutical Grade

Made in Italy

Sealed in Blister Packs for Freshness & Convenience

Suitable for Vegetarians

Contains Nothing Other Than Listed Ingredients

SAMe 400 Brand: Doctor's Best

Rating: 5 stars, based on 2 review(s).
Price: $31.99 - In stock
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Doctor's Best SAMe 400, 400 mg, 30 Tablets Reviews Showing 2 out of 2 reviews for Doctor's Best SAMe 400, 400 mg, 30 Tablets

this product is great, I find it works best w/ vit B!

SAMe 400 review posted by Sarah Zugish  on 9/1/13

I have tried other brand and this is the best!

This SAMe Works for Me

SAMe 400 review posted by Carolyn  on 10/11/12

I take it to elevate my mood, It works great for that. I stay on a pretty even keel through the day. Plus, my joints do not ache and I get around just fine for my 71 years.

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