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Doctor's Best SAMe 200, 200 mg, 60 Tablets

SKU# 753950002067

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List Price: $39.99

$31.99

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($0.53/serving)

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SAMe 200
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Product Highlights
  • Promotes Longevity, Joint Strength, Liver Detoxification, Mood and Brain Function
  • Supports Emotional Well-Being
  • Supports liver health and detoxification
  • Enhances mood and neural function
SKU 753950002067
Quantity 60 Tablets 
Serving Size 1 Tablet
Servings Per Container 60
Potency 200 mg
Dietary Needs Gluten Free
Directions Adults take 1 tablet daily away from food, or as directed by a health care professional. Do not chew or crush tablet.
Warnings SAM-e has an excellent safety profile and is considered well-suited for long term use based on multiple clinical trials. Individuals diagnosed with manic depression should avoid SAM-e supplementation, as it may aggravate the manic phase.
Ingredients …for product label information including a complete list of ingredients, click all product images above.
Product Details

Doctor's Best SAMe 200 mg 60 Enteric Coated Tablets

Suitable for vegetarians

Science-based nutrition

Dietary supplement

Enhances mood and neural function

Promotes joint comfort and mobility

Supports liver health and detoxification

Doctor's Best SAMe 200 mg contains 200 mg of active SAMe in each tablet. Doctor's Best utilizes only the highest quality Italian SAMe available on the market. This ensures that you receive the most potent SAMe product with the highest percentage of the active S,S form per serving, bar none.

S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.

Supplementing with SAMe

The manufacturing process of Doctor's Best SAMe 200 mg yields two forms, the S,S and the R,S isomers. The S,S isomer is the active form that mediates biochemical activity in the human body, whereas the R,S form is considered to be biologically inactive. The Italian SAMe used in our SAMe 200 is processed to yield the highest available percentage of the active pure S,S form on the market.

SAMe and Joint Function

SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential components of connective tissue. Clinical studies show an ability of SAMe to enhance mobility and movement, and promote joint comfort.

SAMe and Neural Health

SAMe-catalyzed methylation reactions promote the synthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function.

SAMe and Liver Function

SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver protection. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.

Individuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.

Ingredients:

Doctor's Best SAMe 200 mg and Double Strength SAM-e 400 contain only the highest quality Italian SAM-e available on the market.  This ensures the most potent SAM-e product with the highest percentage of the active S,S form per serving.

S-Adenosyl Methionine (SAM-e) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system.  Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. Methylation occurs billions of times daily in the many organs of the body. 

SAM-e is involved in numerous biochemical reactions in tissues including the liver, joints and brain.  SAM-e is also required for the biosynthesis of critical neurotransmitters and hormones.  SAM-e is the methyl donor that catalyzes the production of epinephrine, melatonin, glutathione and the amino acids cysteine and taurine.   SAM-e is also known to upregulate the production of critical membrane phospholipids including phosphatidylcholine.  SAM-e is also a sulfur donor and, for this reason, is critical for the formation of sulfur-containing proteoglycans in joint connective tissue.

All SAM-e Supplements are Not Created Equal

During the manufacture of SAM-e, two forms are produced known as the S,S and the R,S isomers. The S,S isomer is the biologically active form in the human body, whereas the R,S form is considered to be inactive. Doctor’s Best SAM-e products utilize Italian SAM-e to yield the highest available percentage of the active pure S,S form on the market.  Doctor’s Best SAM-e contains an average of nearly 74% of the active S,S form.  Other SAM-e products contain as little as only 50% of the active form.  A higher content of the active form yields a more potent product.

The molecule SAM-e itself is highly unstable.  It will degrade quickly in conditions of heat, light and moisture.  To increase its stability, it must be formed into a salt.  It is important to note that SAM-e used for dietary supplements exists in a number of salt forms.  Best SAM-e utilizes the SAM-e tosylate disulfate salt form.  This salt has been the most extensively utilized form in clinical trials of SAM-e.  

Because of the unstable nature of pure SAM-e it is also highly susceptible to degradation in an acidic environment like the stomach.  To be utilized effectively, it must pass through the stomach for absorption in the small intestine.  For this reason, only enteric-coated formulas should be used.  Best SAM-e tablets are enteric-coated to maximize the utilization and benefit of the SAM-e by the body.

SAMe 200 Brand: Doctor's Best

Price: $31.99 - In stock
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